The $0.22 pill and the $10 dose

ED medication went generic years ago. The prices didn't follow — unless you know which door to walk through. Every legitimate channel, priced per dose and per month, fine print included.

The markup, measured: Generic sildenafil 100mg costs $0.22 a tablet at Cost Plus Drugs ($11.94 for 30, delivered) and $10 a dose at Ro — a 45× spread on the same FDA-approved molecule. Subscription telehealth charges roughly 15–45× the cheapest legitimate cash price; the difference buys the consult, the packaging, and the discretion. Amazon's RxPass covers sildenafil entirely for a flat $5/month (tadalafil is not on the list).

Generic sildenafil, as-needed — the markup exhibit

ChannelPriceFine printStatus
Cost Plus Drugs $0.22/tab · $11.94/30 delivered (100 mg) bring your own prescription; $5.25 shipping per order listed price source
Retail + GoodRx coupon $0.39–0.99/tab (Sam's $11.81 → CVS $29.77 per 30) zip- and pharmacy-dependent unconfirmed source
Amazon Pharmacy $0.57/tab with Prime RxPass ($5/mo flat) covers sildenafil; not CA/WA listed price source
Friday Plans ≤$1.99/tab any strength (87¢ promo) TINA.org documented a possible hidden fee gating the promo price — treat with caution until checkout-tested unconfirmed source
Rex MD (LifeMD) 20 mg $2 · 50/100 mg $6 per dose consult free; all sales final listed price source
BlueChew 45 mg chew $3.53–5.00/dose ($30/6 → $120/34) compounded chewable (not FDA-approved as formulated); consult included; cancel anytime listed price source
Hims from ~$4–6/dose; "starting at $22/mo" on long plans $5 processing fee per shipment; cheapest rates need annual prepay; tiers behind intake unconfirmed source
Ro (Roman) 25 mg $4 · 50 mg $6 · 100 mg $10 per dose official per-dose pricing page; $35 minimum order on promo plans listed price source

Daily tadalafil — the same molecule, $11 to $1,045 a month

ChannelPriceFine printStatus
Cost Plus Drugs $11.22/month delivered (5 mg × 30) the cash floor for the daily molecule listed price source
Retail + GoodRx coupon ~$9–19/month zip-dependent unconfirmed source
Amazon Pharmacy ~$13.40–14.80/month with Prime tadalafil NOT on RxPass listed price source
Hims $79/mo monthly → ~$49 quarterly → ~$32 annual site floor "$24/mo"; plan-length tiers behind intake unconfirmed source
Rex MD $2/dose ≈ $60/month daily 2.5/5 mg listed price source
BlueChew DailyTAD $100/mo monthly · $66.67/mo quarterly (9 mg chew + vitamins) compounded listed price source
Ro Daily Rise gummy $89/mo · $69/mo on 3-month (tadalafil 7 mg) compounded gummy; Ro's daily 5 mg tab lists $8/dose — monthly effective unconfirmed unconfirmed source
Brand Cialis 5 mg ~$296 (Amazon) – $433 (avg retail) per month brand reference; Hims brand path $958–1,045/mo unconfirmed source

Brand reference

ChannelPriceFine printStatus
Viagra 100 mg $58–140/tab retail (Amazon $58.13; Ro $90/dose) GoodRx avg retail ~$2,950/30 (50 mg) listed price source
Cialis 5 mg ~$9.88–14.45/tab (Ro $20/dose; 10/20 mg $80) brand premium vs $0.20 generic tadalafil listed price source

The Custom-Formula Tracker — 2-in-1s, 3-in-1s, 4-in-1s

The compounded blends are where composition transparency goes to die: some publish every milligram, some won't name their third ingredient until you've done the intake. We track what's actually in each formula, per dose, per dollar. All are compounded — none is FDA-reviewed as formulated.

FormulaBlendWhat's in itFormatPrice per doseStatus
BlueChew
MAX
2-in-1 sildenafil + tadalafil chew from $5.63/dose listed price source
BlueChew
VMAX
2-in-1 vardenafil + tadalafil chew from $5.63/dose listed price source
BlueChew
GOLD
4-in-1 sildenafil 70–110 mg + tadalafil 18–22 mg + apomorphine + oxytocin sublingual $7.30–18.28/dose (~$75–269/mo by count) listed price source
Hims
Hard Mints 3-in-1
3-in-1 tadalafil + sildenafil + third ingredient unpublished mint ~$8/dose monthly ("from $2" on annual prepay) unconfirmed source
Lemonaid
Bliss
unpublished ingredients not published pre-intake sublingual $8/dose unconfirmed source
Ro
Sparks
2-in-1 sildenafil 55 mg + tadalafil 22 mg sublingual tab $12/dose flat ($48–120/mo by count) listed price source
Rugiet Ready
Rugiet
3-in-1 sildenafil + tadalafil + apomorphine troche $12.42–22.42/dose monthly ($149–269/mo tiers; promo floor ~$7.29) unconfirmed source
BlueChew
DailyTAD
daily tadalafil 9 mg + 7 vitamins daily chew $100/mo monthly · $66.67/mo quarterly listed price source
Ro
Daily Rise
daily tadalafil 7 mg (gummy) daily gummy $89/mo · $69/mo on 3-month listed price source

Composition-transparency rule: formulas that publish full ingredients and doses (Ro Sparks, BlueChew GOLD) get listed-price status; blends with unpublished ingredients stay flagged until an intake walk documents them.

The fine print, collected

How to read this market

Pricing journalism, not medical advice — ED medications have real contraindications (notably nitrates) that belong in a conversation with a clinician. Some links may earn commissions; rankings never bend: disclosure.